
Discover everything you need to know about the best Vex Infinite Damage build in Borderlands 4, including the best weapons, gear, and skills.
Vex Infinite Damage build in Borderlands 4 focuses on turning rift mechanics and crit loops into a damage engine. This setup offers infinite damage in combat. Running this build is fun, and you can use any gun to shred the enemies. Our Vex Infinite Damage build in Borderlands 4 includes skills like Leeching Attunement, Grave Sights, Geistwave, Bloodletter, and more. Also, check out our Vex Bleed Build that focuses on high Bleed damage.
Shotgun is your primary weapon for close-range combat, and Sniper Rifle for long-range combat. Contamination and In The Zone are the best specializations for this setup due to their status effect and critical hit damage. Choose the skill that complements your playstyle and build, allowing you to dominate the enemies. In this guide, we’ll discuss the best Vex Infinite Damage Build in Borderlands 4, including some useful tips and tricks.
Best Skills Vex Infinite Damage Build
Leeching Attunement is all about attuning to kinetic, like the guns that don’t have an element on them. Vex is good at abusing kinetic damage. LifeSteal is nice, but we’ll be converting that LifeSteal to raw gun damage. Bloodletter is the most powerful passive in the game, but certainly Vex’s most powerful passive. This passive allows your crits to have a 505 chance to just tick damage for a percent of your gun damage every second. Energy Vampire is the best Augment to use because it just amps your Bloodletter damage as it counts as a status effect.
Material Components is just more kinetic damage and more kinetic status effect damage. Witchy Trigger Finger ensures that every time you damage something with your F ability while in your Incarnate form, you will gain a stack of Witchy Trigger Finger. Each stack is worth 15% gun damage for 45% at the max stacks. Heartpiercer is best for piercing waves that just everything, giving you stacks easily.

Below are the best Skills, Augment, and Capstone for the Vex Infinite Damage build in Borderlands 4.
| Skills | Points | Bonuses |
|---|---|---|
| Leeching Attunement | 5/5 | Attune Skill. While Vex is attuned to kinetic, she gains increased Lifesteal and reload speed. Effects persist for a duration after attunement is switched. |
| Grave Sights | 5/5 | Kill Skill. Vex gains increased critical hit damage and weapon handling. |
| Geistwave | Augment | Instead of causing a phase explosion, Vex launches a Geistwave, dealing Ordnance damage to enemies it passes through. Each affected takes increased damage for a duration. |
| Bloodletter | 5/5 | Gun and skill critical hits have a chance to apply bleed, causing kinetic status effect damage over time for a duration. Bleed is affected by status effect application chance and is considered a status effect. |
| Energy Vampire | Augment | Vex deals status effect damage to nearby enemies over time and gains overshield for each enemy affected. Kill Skill. Killing an enemy while Incarnate is active will grant a stack of energy vampire, increasing status effect damage. Stacks are lost when the incarnate ends. |
| Grave Implements | 5/5 | Kill Skill. Vex and her minions gain increased gun damage for a duration. |
| Material Components | 5/5 | Vex gains increased kinetic damage and kinetic status effect damage. |
| Grave Power | 3/3 | Vex’s kill skills gain increased max stacks. |
| Grave Harvest | Augment | Kill Skill. Killing an enemy while incarnate is active will spawn a Soul Orb that deals status effect damage over time to nearby enemies for a duration. Detonate a Soul Orb at range by pressing E, dealing Ordnance damage to nearby enemies. Picking up a Soul Orb will restore health and action skill duration. |
| Ars Arcana | 5/5 | Vex gains increased skill damage |
| Essence Leech | 5/5 | Vex gains Lifesteal. Double this effect when an action skill is active. |
| Blood is Power | 3/3 | Vex gains bonus kinetic damage with guns based on Lifesteam when her health is full. |
| Heartpiercer | Capstone | Eldritch blast now sacrifices health on use, but becomes a piercing wave. Enemies hit take damage, and allies hit restore health. Gain bonus damage and healing based on sacrificed health. Eldritch blast no longer has a cooldown. |
| Witchy Trigger Finger | Augment | Dealing damage with Eldritch blast or phase explosion will reload Vex’s current gun and grant a stack of Whitchy trigger Finger, increasing gun damage for a duration. Stacks of Whitchy Trigger Finger persist even after incarnate ends. |
| Iron Maiden | Augment | Phase explosion and Eldritch blasé restore shield for each enemy hit and deal increased damage based on Vex’s current shield. |
| Grave Sustenance | 5/5 | Kill Skill. Restore a percentage of the mission action skill duration. |
| Hasty Fiends | 3/3 | Vex and her minions gain increased movement speed and damage reduction. |
Best Gear For Vex Infinite Damage Build

Extolled Yuga has the single-shot damage as possible. It doesn’t matter what the DPS was; you just need as high a single number there as you can get. Make sure it doesn’t have any modifiers that cancel out the charge at your shots at once, and fire it. For your Repkit, you’re looking for essentially anything with Amp on it. It grants more damage on your next shot.
You can also find just more damage in general after using your Repkit. The best shield for this setup is one with Amp because that’s 100% extra damage on that single big sniper shot when you have Energy Shields.
The issue is that in practice, especially when playing solo, you will be constantly taking damage because you’re the only damage. You want the order one for your enchantment to gain an additional 30% damage on your max fire order shot. Status effect damage, sniper rifle damage, and gun damage are going to be solid for you.
Below are the gear for the Vex Infinite Damage build in Borderlands 4.
| Gear Slot | Item | Bonus |
|---|---|---|
| Shotgun | Hurled Floor- Model Omnibore Husky Friend Vault of Inceptus | Tediore- Thrown Gun homes in and can be shot to increase the explosion’s damage. Jakobs- Critical hits will ricochet projectiles to nearby enemies. Ripper- This gun charges before full auto firing. |
| Sniper Rifle | Extolled Yuga | Can charge up to fire multiple rounds at once. |
| Energy Shield | Amp Calming Bunker | Recharge Rate- When equipped grants a +20% shield recharge rate. Amp- When energy shields are full, shots drain 28% of those shields for +100% gun damage. |
| Enchantment | Excruciating reactive Genesis | Gun damage is increased by +15%. Sniper Rifle damage is increased by 23%. Shotgun status effect chance is increased by +23%. |
| Ordnance | Vampiric Vivisecting Throwing Knife | Damage Amp Payload- Damage taken by the impacted target is increased by +15% for 5s. Penetrator Augment- Damage to the impacted target is are automatic critical hit for 5s. Bloodthirsty- Grenade Lifesteal is increased by 16%. Jakobs- Grenades deal critical damage when hitting weak points. |
| Class Mods | Rending Psion | +28% Submachine gun damage +19% status effect damage +18% reload speed |
| Repkit | Standard Amplified Stim | Speed- On use, grants increased movement speed by +40% for 8s. Amp- On use, grants increased damage for the next shot by +200% |
Best Specialization For Vex Infinite Damage Build

Below are the best specializations for the Vex Infinite Damage build in Borderlands 4.
| Specialization | Bonuses |
| Contamination | Critical hits grant increased status effect application chance. |
| In The Zone | While aiming, the Vault Hunter gains increased gun damage and critical hit damage per second. Bonuses are lost after 2 seconds of not aiming. |
| The Best Defense | The Vault Hunter gains increased damage dealt based on the fullness of their shield or health, whichever has a higher maximum capacity. |
| Riddle You This | Whenever the Vault Hunter deals gun damage, gain a stack of Riddle You This, increasing gun damage. Stacks are lost if a new stack has not been gained for a duration. |
Best Tips and Tricks For Vex Infinite Damage Build
Below are the best tips and tricks for the Vex Infinite Damage Build in Borderlands 4.
- Helps reset cooldowns on Rift faster when defeating enemies in a fight.
- Keeps your elemental bonuses scaling to shred shields.
- Use Shotguns for close-range combat and Sniper rifles for long-range engagements.
- Spec into Survivability nodes early while trying to keep the loop alive.
- Use the Repkits to deal additional gun damage to enemies.
- Pair the damage-dealing skills to deal massive damage with your weapon.
- Take out the weak mobs first when the fight starts, and after that, go for the others.
- Jakobs’ 2x ricochet or stacking damage buff is good while using Hot Slugger.
- Throw a knife at the enemy and then shoot it once.
- Get your order Sniper Rifle out to dominate the mobs from a safe distance.






